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You should not take dabigatran if you are allergic to it, or if you have:

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Dabigatran may cause you to bleed more easily, especially if:

• you have a stomach ulcer;

• you have recent or recurring bleeding in your stomach or intestines;

• you have kidney disease (especially if you also take dronedarone or ketoconazole);

• you take certain other medicines that can increase bleeding risk, such as aspirin, clopidogrel (Plavix), heparin, prasugrel, warfarin (Coumadin, Jantoven);

• you take an NSAID (nonsteroidal anti-inflammatory drug) on a regular basis, such as ibuprofen (Advil, Motrin), naproxen (Aleve), diclofenac, indomethacin, meloxicam, and others; or

• you are older than 75.

Dabigatran can cause a very serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). This type of blood clot could cause long-term paralysis, and may be more likely to occur if:

• you have a genetic spinal defect;

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• you have a history of spinal surgery or repeated spinal taps;

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It is not known whether Pradaxa will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

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Every day, Pfizer colleagues work across developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases of our time. Every day, Pfizer colleagues work across developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases wp login.php?redirect_to=http:trident.legalpradaxa online purchasefeed of our acquisitions, dispositions and other business development activities, and our ability to successfully capitalize on growth opportunities; manufacturing and product candidates, including anticipated regulatory submissions, data read-outs, study starts, approvals, launches, clinical trial results and other. Category: Finance View source version on businesswire.