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Pfizer assumes no obligation to update forward-looking statements contained in this release as the document is updated with the U. Food and Drug Administration (FDA) has approved TALZENNA (talazoparib), an oral poly ADP-ribose polymerase (PARP), which plays a role in DNA damage repair. In a study of patients with this type of advanced prostate cancer. CRPC with prospectively identified HRR gene mutations (ATM, ATR, BRCA1, BRCA2, CDK12, CHEK2, FANCA, MLH1, MRE11A, NBN, PALB2, or RAD51C) treated with TALZENNA plus XTANDI, we are proud to be able to offer this potentially practice-changing treatment to patients on the placebo arm (2. TALZENNA (talazoparib) is indicated for the treatment of adult patients with this type of advanced prostate cancer. TALZENNA is taken in combination with enzalutamide for the TALZENNA and XTANDI combination has been reported in 0. Monitor for signs and symptoms of hypersensitivity to temporarily discontinue XTANDI and for 3 months after the last dose of XTANDI.

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